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Items where Subject is "Biotechnology > Biopharmaceutical Manufacturing and Characterisation"

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Number of items at this level: 65.


Al Nahas, K.; Cama, J.; Schaich, M.; Hammond, K.; Deshpande, S.; Dekker, C.; Ryadnov, M. G.; Keyser, U. F. (2019) A microfluidic platform for the characterisation of membrane active antimicrobials. Lab on a Chip, 19 (5). pp. 837-844. ISSN 1473-0197


Bada Juarez, J F; Judge, P J; Adam, S; Axford, D; Vinals, J; Birch, J; Kwan, T O C; Hoi, K K; Yen, H Y; Vial, A; Milhiet, P E; Robinson, C V; Schapiro, I; Moraes, I; Watts, A (2021) Structures of the archaerhodopsin-3 transporter reveal that disordering of internal water networks underpins receptor sensitization. Nature Communications, 12 (1). 629 ISSN 2041-1723

Bailey, M J A B; Cerasoli, E; Gaines Das, R*; Hills, A; Jones, C*; Kumarswami, N; Lamarre, B; LePevelen, D*; Moore, J D; Nugent, P; Rakowska, P; Robinson, C J*; Silva, M*; Tranter, G*; Wheeler, J* (2007) Strengthening quality control of biopharmaceutical products through the establishment of structure-function relationships. NPL Report. AS 5

Bella, A; Ray, S; Shaw, M; Ryadnov, M G (2012) Arbitrary self-assembly of peptide extracellular microscopic matrices. Angew. Chem. Int. Ed., 51 (2). pp. 428-431.

Birch, J; Axford, D; Foadi, J; Meyer, A; Eckhardt, A; Thielmann, Y; Moraes, I (2018) The fine art of integral membrane protein crystallisation. Methods, 147. pp. 150-162. ISSN 10462023

Burns, J R; Lamarre, B; Pyne, A L B; Noble, J E; Ryadnov, M G (2018) DNA origami inside-out viruses. ACS Synthetic Biology, 7 (3). pp. 767-773. ISSN 2161-5063

Busatto, N; Stolojan, V; Shaw, M; Keddie, J L; Roth, P J (2019) Reactive Polymorphic Nanoparticles: Preparation via Polymerization-Induced Self-Assembly and Postsynthesis Thiol-para -Fluoro Core Modification. Macromolecular Rapid Communications, 40 (2). 1800346 ISSN 10221336


Camacho, I S; Theisen, A; Johannissen, L O; Díaz-Ramos, L A; Christie, J M; Jenkins, G I; Bellina, B; Barran, P; Jones, A R (2019) Native mass spectrometry reveals the conformational diversity of the UVR8 photoreceptor. Proceedings of the National Academy of Sciences, 116 (4). pp. 1116-1125. ISSN 0027-8424

Castelletto, V; de Santis, E; Alkassem, H; Lamarre, B; Noble, J E; Ray, S; Bella, A; Burns, J R; Hoogenboom, B W*; Ryadnov, M G (2016) Structurally plastic peptide capsules for synthetic antimicrobial viruses. Chem. Sci., 7 (3). pp. 1707-1711.

Cerasoli, E; Ravi, J; Gregor, C*; Hussain, R*; Siligardi, G*; Martyna, G*; Crain, J; Ryadnov, M G (2012) Membrane mediated regulation in free peptides of HIV-1 gp41: minimal modulation of the hemifusion phase.. Phys. Chem. Chem. Phys., 14 (3). pp. 1277-1285.

Chatelle, C; Ochoa-Fernandez, R; Engesser, R; Schneider, N; Beyer, H M; Jones, A R; Timmer, J; Zurbriggen, M D; Weber, W (2018) A Green-Light-Responsive System for the Control of Transgene Expression in Mammalian and Plant Cells. ACS Synthetic Biology, 7 (5). pp. 1349-1358. ISSN 2161-5063

Chung, L H C; Birch, D J S; Vyshemirsky, V; Bella, A; Ryadnov, M G; Rolinski, O J (2019) Protein fibrillogenesis model tracked by its intrinsic time-resolved emission spectra. Methods and Applications in Fluorescence, 7 (3). 035003 ISSN 2050-6120

Cipcigan, F; Carrieri, A P; Pyzer-Knapp, E O; Krishna, R; Hsiao, Y-W; Winn, M; Ryadnov, M G; Edge, C; Martyna, G; Crain, J (2018) Accelerating molecular discovery through data and physical sciences: Applications to peptide-membrane interactions. The Journal of Chemical Physics, 148 (24). 241744 ISSN 0021-9606

Claveau, R; Manescu, P; Fernandez-Reyes, D; Shaw, M (2020) Structure-dependent amplification for denoising and background correction in Fourier ptychographic microscopy. Optics Express, 28 (24). 35438 ISSN 1094-4087

Cox, M G; Ravi, J; Rakowska, P D; Knight, A E (2014) Uncertainty in measurement of protein circular dichroism spectra. Metrologia, 51 (1). pp. 67-79.


de Santis, E; Alkassem, H; Lamarre, B; Faruqui, N; Bella, A; Noble, J E; Micale, N; Ray, S; Burns, J R; Yon, A R; Hoogenboom, B W; Ryadnov, M G (2017) Antimicrobial peptide capsids of de novo design. Nature Communications, 8. 2263

de Santis, E; Ryadnov, M G (2015) Peptide self-assembly for nanomaterials: the old new kid on the block. Chem. Soc. Rev., 44 (22). pp. 8288-8300.


Elmi, M; Pawar, V M; Shaw, M; Wong, D; Zhan, H Y; Srinivasan, M A (2017) Determining the biomechanical of touch sensation in C. elegans. Scientific Reports, 7. 12329


Giraud, G*; Pethig, R*; Schulze, H*; Henihan, G*; Terry, J G*; Menachery, A*; Ciani, I*; Corrigan, D*; Campbell, C J*; Mount, A R*; Ghazal, P*; Walton, A J*; Crain, J; Bachmann, T T* (2011) Dielectrophoretic manipulation of ribosomal RNA. Biomicrofluidics, 5 (2). 024116


Halliwell, C M; Green, F; Gilmore, I S; Cumpson, P J; Davies, J A (2004) Nanoanalytical measurements for the determination of protein orientation at surfaces. The Analyst, 129. pp. 1166-1170.

Hammond, K; Lewis, H; Faruqui, N; Russell, C; Hoogenboom, B W; Ryadnov, M G (2019) Helminth Defense Molecules as Design Templates for Membrane Active Antibiotics. ACS Infectious Diseases, 5 (8). pp. 1471-1479. ISSN 2373-8227

Hammond, K; Ryadnov, M G; Hoogenboom, B W (2021) Atomic force microscopy to elucidate how peptides disrupt membranes. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1863 (1). 183447 ISSN 00052736

Harvey, D J*; Crispin, M*; Scanlan, C*; Singer, B B*; Lucka, L*; Chang, V T*; Radcliffe, C M*; Thobhani, S; Yuen, C-T*; Rudd, P M* (2008) Differentiation between isomeric triantennary N-linked glycans by negative ion tandem mass spectrometry and confirmation of glycans containing galactose attached to the bisecting ß(1-4-GlcNAc) residue in N-glycans from IgG. Rapid Commun. Mass Spectrom., 22 (7). pp. 1047-1052.


Iavicoli, P*; Rossi, F*; Lamarre, B; Bella, A; Ryadnov, M G; Calzolai, L* (2017) Modulating charge-dependent and folding-mediated antimicrobial interactions at peptide-lipid interfaces. Eur. Biophys. J. with Biophys. Lett., 46 (4). pp. 375-382.


Judge, P; Juarez, J B; Vinals, J; Axford, D; Moraes, I; Watts, A (2019) Destabilisation of internal water networks underpins the sensitisation of a membrane-embedded photoreceptor protein: structures of dark- and light-adapted Archaerhodopsin-3 Irtransporter to atomic resolution. European Biophysic Journal with Biophysics Letters, 48. S174.


Kepiro, I E; Nardone, B; Page, A; Ryadnov, M G (2020) Revealing Sources of Variation for Reproducible Imaging of Protein Assemblies by Electron Microscopy. Micromachines, 11 (3). 251 ISSN 2072-666X

Kitney, R; Adeogun, M; Fujishima, Y; Goñi-Moreno, A; Johnson, R; Maxon, M; Steedman, S; Ward, S; Winickoff, D; Philp, J (2019) Enabling the Advanced Bioeconomy through Public Policy Supporting Biofoundries and Engineering Biology. Trends in Biotechnology, 37 (9). pp. 917-920. ISSN 01677799

Kotov, V; Bartels, K; Veith, K; Josts, I; Subhramanyam, U K T; Günther, C; Labahn, J; Marlovits, T C; Moraes, I; Tidow, H; Löw, C; Garcia-Alai, M M (2019) High-throughput stability screening for detergent-solubilized membrane proteins. Scientific Reports, 9 (1). 10379 ISSN 2045-2322

Kwan, T O C; Axford, D; Moraes, I (2020) Membrane protein crystallography in the era of modern structural biology. Biochemical Society Transactions, 48 (6). pp. 2505-2524. ISSN 0300-5127


Marzuoli, I; Lorenz, M; Ryadnov, M G; Fraternali, F (2017) A computational approach to self-assembly of new antimicrobial peptides. European Biophysics Journal with Biophysics Letters, 46 (Supp 1). S223.

Mather, M; Tomlins, P E (2010) Hydrogels in regenerative medicine: towards understanding structure-function relationships. Regenerative Med., 5 (5). pp. 809-821.

Moore, J D; Noble, J E; Nugent, P G; Cerasoli, E; Lamarre, B M; Bailey, M J A (2007) Towards the development of protein-protein interaction standards to improve the comparability of protein interaction measurements. NPL Report. AS 8

Moore, J D; Perez-Pardo, M A*; Popplewell, J F*; Spencer, S J; Ray, S; Swann, M J*; Shard, A G; Jones, W*; Hills, A*; Bracewell, D G* (2011) Chemical and biological characterisation of a sensor surface for bioprocess monitoring. Biosens. Bioelectron., 26 (6). pp. 2940-2947.

Moraes, I; Quigley, A (2021) Structural Biology and Structure–Function Relationships of Membrane Proteins. Biology, 10 (3). 245 ISSN 2079-7737


Noble, J E (2014) Quantification of protein concentration using UV absorbance and coomassie dyes. Methods in Enzymology, 536. pp. 17-26.

Noble, J E; Bailey, M J A* (2009) Quantitation of protein. Methods in Enzymology, 463. pp. 73-95.

Noble, J E; Cerasoli, E (2007) Fluorescent labelling of protein analysis. NPL Report. AS 10

Noble, J E; Knight, A E; Reason, A J*; Di Matola, A*; Bailey, M J A (2007) Protein quantitation assays for biopharmaceutical applications. NPL Report. AS 11

Noble, J E; Knight, A E; Reason, A J*; Di Matola, A*; Bailey, M J A (2007) A comparison of protein quantitation assays for biopharmaceutical applications. Mol. Biotechnol., 37 (2). pp. 99-111.

Noble, J E; Wang, L*; Cole, K D*; Gaigalas, A K* (2005) The effect of overhanging nucleotides on fluorescence properties of hybridising oligonucleotides labelled with Alexa 488 and FAM fluorophores. Biophysical Chemistry, 113. pp. 255-263.


Pfeil, M P; Pyne, A L B; Losasso, V; Ravi, J; Lamarre, B; Faruqui, N; Alkassem, H; Hammond, K; Judge, P J; Winn, M; Martyna, G J; Crain, J; Watts, A; Hoogenboom, B W; Ryadnov, M G (2018) Tuneable poration: host defense peptides as sequence probes for antimicrobial mechanisms. Scientific Reports, 8 (1). 14926 ISSN 2045-2322

Philpott, D J; Doorduijn, D J; Bardoel, B W; Heesterbeek, D A C; Ruyken, M; Benn, G; Parsons, E S; Hoogenboom, B W; Rooijakkers, S H M (2020) Bacterial killing by complement requires direct anchoring of membrane attack complex precursor C5b-7. PLOS Pathogens, 16 (6). e1008606 ISSN 1553-7374

Piarali, S; Marlinghaus, L; Viebahn, R; Lewis, H; Ryadnov, M G; Groll, J; Salber, J; Roy, I (2020) Activated Polyhydroxyalkanoate Meshes Prevent Bacterial Adhesion and Biofilm Development in Regenerative Medicine Applications. Frontiers in Bioengineering and Biotechnology, 8. 442 ISSN 2296-4185

Povey, M J W*; Moore, J D; Braybrook, J*; Simons, H*; Belchamber, R*; Raganathan, M*; Pinfield, V* (2011) Investigation of bovine serum albumin denaturation using ultrasonic spectroscopy. Food Hydrocolloids, 25 (5). pp. 1233-1241.

Pyne, A; Pfeil, M P; Bennett, I*; Ravi, J; Iavicoli, P*; Lamarre, B; Roethke, A*; Ray, S; Jiang, H B*; Bella, A; Reisinger, B*; Yin, D; Little, B*; Munoz-Garcia, J C*; Cerasoli, E; Judge, P J*; Faruqui, N; Calzolai, L*; Henrion, A*; Martyna, G J*; Grovenor, C R M*; Crain, J; Hoogenboom, B W*; Watts, A*; Ryadnov, M G (2017) Engineering monolayer poration for rapid exfoliation of microbial membranes. Chem. Sci., 8 (2). pp. 1105-1115.

Pyne, A L B; Pfeil, M P; Bennett, I; Ravi, J; Lamarre, B; Hoogenboom, B W; Ryadnov, M (2017) Investigating the mechanism of action of a novel antimicrobial peptide on live E. coli cells. European Biophysics Journal with Biophysics Letters, 46. S389.


Ravi, J; Hills, A E; Knight, A E (2009) Reproducible circular dichroism measurements for biopharmaceutical applications. Volume 1 Advances in Biomedical Spectroscopy. In: Modern Techniques for Circular Dichroism and Synchrotran Radiation Circular Dichroism Spectroscopy. UNSPECIFIED, pp. 125-140. ISBN 9781607500001

Ravi, J; LePevelen, D*; Tranter, G*; Knight, A (2007) Higher-order protein structure measurements for biopharmaceutical quality control. NPL Report. AS 9

Ravi, J; Pfeil, M P; Pyne, A L (2019) Probing antimicrobial mechanisms for effective strategies to overcome resistance. European Biophysics Journal with Biophysics Letters, 48. S223.

Ravi, J; Rakowska, P; Garfagnini, T; Baron, B*; Charlet, P*; Jones, C*; Milev, S*; DeSa Lorenz, J*; Plusquellic, D*; Wein, F*; Liqing Wu*,, ; Meuse, C W*; Knight, A E (2010) International comparability in spectroscopic measurements of protein structure by circular dichroism: CCQM-P59.1. Metrologia, 47 (6). pp. 631-641.

Ravi, J; Schiffmann, D; Tantra, R; Cox, S; Eady, J; Jones, C*; Vrettos, J S*; Affleck, R P*; DeSa Lorenz, J*; Shigeri, Y*; Linghui, S*; Jun, L*; Willows, R*; Charlet, P*; Dupont, Y*; Meuse, C W*; Bailey, M J A; Knight, A E (2010) International comparability in spectroscopic measurements of protein structure by circular dichroism: CCQM-P59. Metrologia, 47 (1A). 08022.

Ravi, J; Tantra, R; Knight, A (2005) Techniques for the measurement of the structure of proteins in solution, and their complementarity to circular dichroism. NPL Report. DQL-AS 023

Reis, R; Moraes, I (2019) Structural biology and structure–function relationships of membrane proteins. Biochemical Society Transactions, 47 (1). pp. 47-61. ISSN 0300-5127

Rodger, A; Marrington, R*; Roper, D I*; Windsor, S A (2005) Circular dichroism spectroscopy for the study of protein ligand interactions. In: Protein-ligand interactions: methods and protocols. Humana Press Inc, pp. 343-364. ISBN 1588293726

Ryadnov, M G; Cerasoli, E; Martyna, G J*; Crain, J (2010) Translational biophysics: the physical sciences in molecular medicine. Future Med. Chem., 2 (11). pp. 1633-1639.

Ryadnov, M G; Cherny, D I* (2012) Natively unfolded state for engineering nanoscale fibrillar arrays. Macromol. Biosci., 12 (2). pp. 195-201.


Shaw, M; O'Holleran, K; Paterson, C* (2013) Investigation of the confocal wavefront sensor and its application to biological microscopy. Opt. Express, 21 (16). pp. 19353-19362.

Shaw, M J; Zajiczek, L; O'Holleran, K* (2015) High speed structured illumination microscopy in optically thick samples. Methods, 88. pp. 11-19.

Silva, M M C G*; Lamarre, B; Cerasoli, E; Rakowska, P; Hills, A; Bailey, M J A; Wheeler, J X*; Burns, C J*; Gaines-Das, R E*; Jones, C*; Robinson, C J* (2008) Physicochemical and biological assays for quality control of biopharmaceuticals: Interferon alfa-2 case study. Biologicals, 36 (6). pp. 383-392.

Simcock, P W; Bublitz, M; Cipcigan, F; Ryadnov, M G; Crain, J; Stansfeld, P J; Sansom, M S P (2021) Membrane Binding of Antimicrobial Peptides Is Modulated by Lipid Charge Modification. Journal of Chemical Theory and Computation, 17 (2). pp. 1218-1228. ISSN 1549-9618


Tangbunsuk, S*; Whittell, G R*; Ryadnov, M G; Vandermeulen, G W M*; Woolfson, D N*; Manners, I* (2012) Metallopolymer-peptide hydrid materials: synthesis and self-assembly of functional, polyferrocenylsilane-tetrapeptide conjugates. Chem. Eur. J., 18 (9). pp. 2524-2535.

Thobhani, S; Bailey, M; Yuen, C-T*; Jones, C* (2007) Characterisation and quantitation of post-translationally modified proteins. NPL Report. AS 6

Thobhani, S; Yuen, C T*; Bailey, M J A; Jones, C* (2009) Identification and quantification of N-linked oligosaccharides released from glycoproteins: An inter-laboratory study. Glycobiology, 19 (3). pp. 201-211.


Valsesia, A*; Iavicoli, P*; Lewis, H; Desmet, C*; Mehn, D*; Calzolai, L*; Colpo, P*; Rossi, F*; Ryadnov, M G (2017) Nano-mechanical in-process monitoring of antimicrobial poration in model phospholipid bilayers. RSC Adv., 7 (31). pp. 19081-19084.


Whitehouse, W L; Noble, J E; Ryadnov, M G; Howorka, S (2019) Cholesterol Anchors Enable Efficient Binding and Intracellular Uptake of DNA Nanostructures. Bioconjugate Chemistry, 30 (7). pp. 1836-1844. ISSN 1043-1802

This list was generated on Mon Oct 25 08:59:12 2021 BST.