Palmans, Hugo; Carlino, Antonio; Gouldstone, Clare; Sharpe, Peter (2018) Cross calibration of alanine for scanned proton beams. NPL Report. IR 48

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Abstract

Alanine is a suitable dosimeter for absolute dosimetry, dose verification, end-to-end dosimetry and dosimetric audit of clinical proton beams. For establishing traceability to primary standards of absorbed dose to water, NPL¿s alanine dosimeter is calibrated in a 60Co photon beam. The energy dependence of the alanine response in proton beams has been well understood but a systematic difference of about 2% between the alanine response in high-energy proton beams and its response in a 60Co photon beams has been demonstrated. For this reason we propose to cross calibrate the alanine dosimeter in a high-energy proton beam for its use in any clinical proton beam. This report presents the results of the cross calibration of alanine detectors in a high-energy scanned proton beam at MedAustron. The cross-calibration establishes a value of the beam quality correction factor and its uncertainty. The report also details how the alanine dosimeters should subsequently be used in clinical proton beams different from the cross-calibration beam quality.

Item Type:	Report/Guide (NPL Report)
NPL Report No.:	IR 48
Subjects:	Ionising Radiation > Dosimetry
Divisions:	Chemical, Medical & Environmental Science
Last Modified:	29 Oct 2018 10:32
URI:	https://eprintspublications.npl.co.uk/id/eprint/8118