Brown, R J C; Milton, M J T; Gallop, J C (2001) Review of techniques for single molecule detection in biological applications. NPL Report. COAM 2

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Abstract

This report reviews various experimental techniques that have the potential to detection single molecules and highlights their possible application to the detection of biomolecules. These have been grouped into two categories within the report; Scanning Probe Microscopies (SPMs), those methods yielding force and current data, and Applied Optical Spectroscopies, those techniques providing optical and spectroscopic information. The theory of each technique is described along with relevant current research and the requirements that each technique might generate for further measurement research.

Item Type:	Report/Guide (NPL Report)
NPL Report No.:	COAM 2
Subjects:	Analytical Science
Last Modified:	02 Feb 2018 13:17
URI:	https://eprintspublications.npl.co.uk/id/eprint/2103