< back to main site

Publications

Determination of the 161Tb half-life

Collins, S M; Gilligan, C; Pierson, B; Ramirez, N; Goodwin, M; Pearce, A K; Archambault, B C; Haney, M M; Regan, P H (2022) Determination of the 161Tb half-life. Applied Radiation and Isotopes, 182. 110140

Full text not available from this repository.

Abstract

There is significant interest in the use of terbium radioisotopes for applications in cancer therapy and diagnosis. Of these, 161Tb, as a medium energy beta-emitter, is being investigated as a potential alternative to 177Lu. The relatively high proportion of conversion electron and Auger electron emissions per decay make 161Tb an attractive targeted therapeutic. As a product of nuclear fission, 161Tb is also of importance to nuclear forensics. The standard uncertainty of the current evaluated half-life of 6.89(2) d contributes significantly to the standard uncertainty of any decay corrected activity determination made. Furthermore, the accuracy of this evaluated half-life has been called into question by measurements reported in 2020 at the Institute of Radiation Physics (IRP), Switzerland, who reported a half-life of 6.953(2) d. In the current work, the half-life of the 161Tb ground state decay has been measured at three independent laboratories located in the United Kingdom and the United States of America for a total of six determinations using three independent measurement techniques; gamma-ray spectrometry, ionisation chamber and liquid scintillation counting. The half-life determined for 161Tb of 6.9637(29) d confirms the observed 1 % relative increase observed by IRP, though the reported half-lives in this work and at IRP are significantly different (zeta-score = 3.1).

Item Type: Article
Subjects: Ionising Radiation > Radioactivity
Divisions: Medical, Marine & Nuclear
Identification number/DOI: 10.1016/j.apradiso.2022.110140
Last Modified: 11 Apr 2022 13:58
URI: http://eprintspublications.npl.co.uk/id/eprint/9410

Actions (login required)

View Item View Item