Carlino, A; Palmans, H; Gouldstone, C; Trnkova, P; Noerrevang, O; Vestergaard, A; Freixas, G V; Bosmans, G; Lorentini, S; Schwarz, M; Koska, B; Wulff, J; Vatnitsky, S; Stock, M (2021) Results of an independent dosimetry audit for scanned proton beam therapy facilities. Zeitschrift fur Medizinische Physik, 31 (2). pp. 145-153.

Full text not available from this repository.

Abstract

Purpose: An independent dosimetry audit based on end-to-end testing of the entire chain of radiation therapy delivery is highly recommended to ensure consistent treatments among proton therapy centers. This study presents an auditing methodology developed by the MedAustron Ion Beam Therapy Center (Austria) in collaboration with the National Physical Laboratory (UK) and audit results for five scanned proton beam therapy facilities in Europe.

Methods: The audit procedure used a homogeneous and an anthropomorphic head phantom. The phantoms were loaded either with an ionization chamber or with alanine pellets and radiochromic films. Homogeneously planned doses of 10 Gywere delivered to a box-like target volume in the homogeneous phantom and to two clinical scenarios with increasing complexity in the head phantom.

Results: For all tests the mean of the local differences of the absolute dose to water determined with the alanine pellets compared to the predicted dose from the treatment planning system installed at the audited institution was determined. The mean value taken over all tests performed was −0.1 ± 1.0%. The measurements carried out with the ionization chamber were consistent with the dose determined by the alanine pellets with a mean deviation of −0.5 ± 0.6%.

Item Type:	Article
Keywords:	Proton therapy, Dosimetry audit, End-to-end test, Alanine dosimeters, Ionization chamber
Subjects:	Ionising Radiation > Dosimetry
Divisions:	Medical, Marine & Nuclear
Identification number/DOI:	10.1016/j.zemedi.2021.01.003
Last Modified:	05 May 2023 13:35
URI:	https://eprintspublications.npl.co.uk/id/eprint/9397