Galer, S; Shipley, D R; Palmans, H; Kirkby, K J; Nisbet, A (2017) Monte Carlo simulation of a TEPC for microdosimetry of carbon ions. Radiation Physics and Chemistry, 140. pp. 412-418.

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Abstract

The increase in the number of therapeutic proton and ion beam centres worldwide has prompted new interest in measuring and simulating microdosimetric spectra as part of understanding the complexity underlying the relative biological effectiveness (RBE) of these treatment modalities. In this context we have studied the capability of the Geant4 toolkit to simulate microdosimetric spectra measured with a Tissue Equivalent Proportional Counter (TEPC). The simulated spectra were compared with experimental data obtained along the Bragg peak curve of a 194 MeV/u carbon beam at the GSI, Darmstadt, which were published by Gerlach et al. The initial beam energy and energy spread used in the simulation were tuned to match the calculated and measured depth dose distributions. A good agreement was found at all depths showing that the Geant4 toolkit can be used for simulating microdosimetric spectra obtained with a TEPC. This work also shows that the data from Gerlach et al. could serve as a benchmark for Monte Carlo simulation provided the initial energy and energy spread is tuned to match the depth dose distributions and an additional shift of the position of the TEPC is taken into account.

Item Type:	Article
Keywords:	Microdosimetry, TEPC, Monte Carlo
Subjects:	Ionising Radiation > Dosimetry
Divisions:	Chemical, Medical & Environmental Science
Identification number/DOI:	10.1016/j.radphyschem.2017.02.028
Last Modified:	15 Feb 2018 15:08
URI:	https://eprintspublications.npl.co.uk/id/eprint/7718