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Metrological issues in molecular radiotherapy.

D'Arienzo, M*; Capogni, M*; Smyth, V*; Cox, M G; Johansson, L C; Solc, J*; Bobin, C*; Rabus, H*; Joulaeizedeh, L* (2014) Metrological issues in molecular radiotherapy. EPJ Web of Conferences, 77. 00022.

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Abstract

The therapeutic effect from molecular radiation therapy (MRT), on both tumour and normal tissue, is determined by the radiation absorbed dose. Recent research indicates that as a consequence of biological variation across patients the absorbed dose can vary, for the same administered activity, by as much as two orders of magnitude. The international collaborative EURAMET-The therapeutic effect from molecular radiation therapy (MRT), on both tumour and normal tissue, is determined by the radiation absorbed dose. Recent research indicates that as a consequence of biological variation across patients the absorbed dose can vary, for the same administered activity, by as much as two orders of magnitude. The international collaborative EURAMET-EMRP project "Metrology for molecular radiotherapy (MetroMRT)" is addressing this problem. The overall aim of the project is to develop methods of calibrating and verifying clinical dosimetry in MRT. In the present paper an overview of the metrological issues in molecular radiotherapy is provided.

Item Type: Article
Keywords: molecular radiation therapy, absorbed dose, EMRP, MetroMRT, metrology, modelling, measurement uncertainty
Subjects: Ionising Radiation
Ionising Radiation > Radioactivity
Identification number/DOI: 10.1051/epjconf/20147700022
Last Modified: 02 Feb 2018 13:13
URI: http://eprintspublications.npl.co.uk/id/eprint/6614

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