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The rational development of molecularly imprinted polymer-based sensors for protein detection.

Whitcombe, M J*; Chianella, I*; Larcombe, L*; Piletsky, S A*; Noble, J E; Porter, R A; Horgan, A (2011) The rational development of molecularly imprinted polymer-based sensors for protein detection. Chem. Soc. Rev., 40 (3). pp. 1547-1571.

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Abstract

The detection of specific proteins as biomarkers of disease, health status, environmental monitoring, food quality, control of fermenters and civil defence purposes means that biosensors for these targets will become increasingly more important. Among the technologies used for building specific recognition properties, molecularly imprinted polymers (MIPs) are attracting much attention. In this critical review we describe many methods used for imprinting recognition for protein targets in polymers and their incorporation with a number of transducer platforms with the aim of identifying the most promising approaches for the preparation of MIP-based protein sensors

Item Type: Article
Subjects: Biotechnology
Biotechnology > Bio-Diagnostics
Identification number/DOI: 10.1039/C0CS00049C
Last Modified: 02 Feb 2018 13:14
URI: http://eprintspublications.npl.co.uk/id/eprint/4904

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