Lam, J K; Winkless, L; Shard, A G; Tomlins, P E (2008) On the preparation of textured surfaces for cell adhesion/differentiation studies. NPL Report. MAT 14

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Abstract

The behaviour of cells on surfaces is complex and dependent on the surface chemistry, surface topography, the age and type of cell as well as the number of population doublings and the culture conditions. It has been shown that almost any result can be obtained in terms of assessing biocompatibility through cell attachment to a surface by adjusting these variables.

In this report we describe methods of manufacturing surfaces with micrometre or nanometre features in metal, plastic and an inorganic material and describe some of the techniques that can be used to characterise them. These surfaces can be used to investigate adhesion of cells to surfaces or for measurements of protein adsorption.

Item Type:	Report/Guide (NPL Report)
NPL Report No.:	MAT 14
Keywords:	surface topography, micrometre scale, nanoscale, characterisation, biocompatability
Subjects:	Advanced Materials
Last Modified:	02 Feb 2018 13:15
URI:	http://eprintspublications.npl.co.uk/id/eprint/4115

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