Lam, J; Penn, D; Tomlins, P E (2007) Measurement of flow induced strain in a mechanically active bioreactor. NPL Report. DEPC-MPR 059

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Abstract

It is becoming increasing apparent that the cells being cultured in vitro to form replacement viable tissues for use in medicine require some degree of mechanical stimulation to maintain their phenotype. Ideally this should mimic the conditions found in vivo. New designs of bioreactor are being designed to be able to provide mechanical stimulation to cell-seeded scaffolds but exactly how this is transferred to specimens has not been widely studied. In this report we compare two approaches for mapping flow induced dilation of a tubular structure in a biodynamic chamber designed for cardiovascular tissue engineering. These are digital image correlation and laser micrometry.

Item Type:	Report/Guide (NPL Report)
NPL Report No.:	DEPC-MPR 059
Keywords:	dynamic strain, tissue engineering
Subjects:	Advanced Materials Advanced Materials > Biomaterials
Last Modified:	02 Feb 2018 13:15
URI:	http://eprintspublications.npl.co.uk/id/eprint/3785

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