< back to main site

Publications

Observation of dynamic oxygen release in hemoglobin using surface Raman scattering.

Etchegoin, P*; Liem, H*; Maher, R C*; Cohan, L F*; Brown, R J C; Milton, M J T; Gallop, J C (2003) Observation of dynamic oxygen release in hemoglobin using surface Raman scattering. Chem. Phys. Lett., 367 (1-2). pp. 223-229.

Full text not available from this repository.

Abstract

Photinduced oxygen dynamics in hemoglobin is monitored by surface enhanced resonant Raman spectroscopy (SERRS) using silver colliods. The spectra are characterized by massive transient amplifications which we assign to a charge-transfer mechanism during the opening of the heme-pockets in the release of oxygen. This transient lifts the selection rule specificity of normal Raman active modes and allows for the full density of states of the hemes to be observed. The amplification of specific forbidden modes is controlled by the orientation alignment if individual molecules in proximity with the colloid surface. We propose that the technique can be used to monitor oxygen release in single proteins.

Item Type: Article
Subjects: Biotechnology
Biotechnology > Bio-Diagnostics
Last Modified: 02 Feb 2018 13:16
URI: http://eprintspublications.npl.co.uk/id/eprint/2512

Actions (login required)

View Item View Item